| 2026-08-15 | UFC 330: Makhachev vs. Machado Garry | Middleweight | Tresean Gore def. Vicente Luque | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2026-04-11 | UFC 327: Procházka vs. Ulberg | Middleweight | Vicente Luque def. Kelvin Gastelum | Submission (anaconda choke) | 1 | 4:08 |
| 2025-10-11 | UFC Fight Night: Oliveira vs. Gamrot | Welterweight | Joel Álvarez def. Vicente Luque | Decision (unanimous) (30–26, 30–26, 30–26) | 3 | 5:00 |
| 2025-06-07 | UFC 316: Dvalishvili vs. O'Malley 2 | Welterweight | Kevin Holland def. Vicente Luque | Submission (anaconda choke) | 2 | 1:03 |
| 2024-12-07 | UFC 310: Pantoja vs. Asakura | Welterweight | Vicente Luque def. Themba Gorimbo | Technical Submission (anaconda choke) | 1 | 0:52 |
| 2024-03-30 | UFC on ESPN: Blanchfield vs. Fiorot | Welterweight | Joaquin Buckley def. Vicente Luque | TKO (punches) | 2 | 3:17 |
| 2023-08-12 | UFC on ESPN: Luque vs. dos Anjos | Welterweight | Vicente Luque def. Rafael dos Anjos | Decision (unanimous) (49–46, 48–47, 48–47) | 5 | 5:00 |
| 2022-08-06 | UFC on ESPN: Santos vs. Hill | Welterweight | Geoff Neal def. Vicente Luque | KO (punches) | 3 | 2:01 |
| 2022-04-16 | UFC on ESPN: Luque vs. Muhammad 2 | Welterweight | Belal Muhammad def. Vicente Luque | Decision (unanimous) (49–46, 49–46, 48–47) | 5 | 5:00 |
| 2021-08-07 | UFC 265: Lewis vs. Gane | Welterweight | Vicente Luque def. Michael Chiesa | Submission (D’Arce choke) | 1 | 3:25 |
| 2021-03-27 | UFC 260: Miocic vs. Ngannou 2 | Welterweight | Vicente Luque def. Tyron Woodley | Submission (brabo choke) | 1 | 3:56 |
| 2020-08-01 | UFC Fight Night: Brunson vs. Shahbazyan | Welterweight | Vicente Luque def. Randy Brown | KO (knee and punches) | 2 | 4:56 |
| 2020-05-09 | UFC 249: Ferguson vs. Gaethje | Welterweight | Vicente Luque def. Niko Price | TKO (doctor stoppage) | 3 | 3:37 |
| 2019-11-02 | UFC 244: Masvidal vs. Diaz | Welterweight | Stephen Thompson def. Vicente Luque | Decision (unanimous) (30–26, 30–26, 29–27) | 3 | 5:00 |
| 2019-08-10 | UFC Fight Night: Shevchenko vs. Carmouche 2 | Welterweight | Vicente Luque def. Mike Perry | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2019-05-18 | UFC Fight Night: dos Anjos vs. Lee | Welterweight | Vicente Luque def. Derrick Krantz | TKO (punches) | 1 | 3:52 |
| 2019-02-17 | UFC on ESPN: Ngannou vs. Velasquez | Welterweight | Vicente Luque def. Bryan Barberena | TKO (knees and punches) | 3 | 4:54 |
| 2018-10-06 | UFC 229: Khabib vs. McGregor | Welterweight | Vicente Luque def. Jalin Turner | KO (punches) | 1 | 3:52 |
| 2018-05-19 | UFC Fight Night: Maia vs. Usman | Welterweight | Vicente Luque def. Chad Laprise | KO (punches) | 1 | 4:16 |
| 2017-10-28 | UFC Fight Night: Brunson vs. Machida | Welterweight | Vicente Luque def. Niko Price | Submission (D'arce choke) | 2 | 4:08 |
| 2017-03-18 | UFC Fight Night: Manuwa vs. Anderson | Welterweight | Leon Edwards def. Vicente Luque | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2016-11-12 | UFC 205: Alvarez vs. McGregor | Welterweight | Vicente Luque def. Belal Muhammad | KO (punches) | 1 | 1:19 |
| 2016-09-24 | UFC Fight Night: Cyborg vs. Länsberg | Welterweight | Vicente Luque def. Héctor Urbina | KO (punch) | 1 | 1:00 |
| 2016-07-07 | UFC Fight Night: dos Anjos vs. Alvarez | Welterweight | Vicente Luque def. Álvaro Herrera | Submission (D'Arce choke) | 2 | 3:52 |
| 2015-12-19 | UFC on Fox: dos Anjos vs. Cowboy 2 | Welterweight | Vicente Luque def. Hayder Hassan | Technical Submission (anaconda choke) | 1 | 2:13 |
| 2015-07-12 | The Ultimate Fighter: American Top Team vs. Blackzilians Finale | Welterweight | Michael Graves def. Vicente Luque | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |