| 2024-03-16 | UFC Fight Night: Tuivasa vs. Tybura | Middleweight | Gerald Meerschaert def. Bryan Barberena | Technical Submission (face crank) | 2 | 4:23 |
| 2023-07-22 | UFC Fight Night: Aspinall vs. Tybura | Middleweight | Makhmud Muradov def. Bryan Barberena | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2023-03-18 | UFC 286: Edwards vs. Usman 3 | Welterweight | Gunnar Nelson def. Bryan Barberena | Submission (armbar) | 1 | 4:51 |
| 2022-12-03 | UFC on ESPN: Thompson vs. Holland | Welterweight | Rafael dos Anjos def. Bryan Barberena | Submission (neck crank) | 2 | 3:20 |
| 2022-07-02 | UFC 276: Adesanya vs. Cannonier | Welterweight | Bryan Barberena def. Robbie Lawler | TKO (punches) | 2 | 4:47 |
| 2022-03-26 | UFC on ESPN: Blaydes vs. Daukaus | Welterweight | Bryan Barberena def. Matt Brown | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2021-12-04 | UFC on ESPN: Font vs. Aldo | Welterweight | Bryan Barberena def. Darian Weeks | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2021-07-31 | UFC on ESPN: Hall vs. Strickland | Welterweight | Jason Witt def. Bryan Barberena | Decision (majority) (28–28, 29–27, 29–28) | 3 | 5:00 |
| 2020-09-12 | UFC Fight Night: Waterson vs. Hill | Welterweight | Bryan Barberena def. Anthony Ivy | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2019-06-22 | UFC Fight Night: Moicano vs. The Korean Zombie | Welterweight | Randy Brown def. Bryan Barberena | TKO (punches) | 3 | 2:54 |
| 2019-02-17 | UFC on ESPN: Ngannou vs. Velasquez | Welterweight | Vicente Luque def. Bryan Barberena | TKO (knees and punches) | 3 | 4:54 |
| 2018-08-25 | UFC Fight Night: Gaethje vs. Vick | Welterweight | Bryan Barberena def. Jake Ellenberger | TKO (punches) | 1 | 2:26 |
| 2017-09-02 | UFC Fight Night: Volkov vs. Struve | Welterweight | Leon Edwards def. Bryan Barberena | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2017-04-22 | UFC Fight Night: Swanson vs. Lobov | Welterweight | Bryan Barberena def. Joe Proctor | TKO (knees and punches) | 1 | 3:30 |
| 2016-12-17 | UFC on Fox: VanZant vs. Waterson | Welterweight | Colby Covington def. Bryan Barberena | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2016-05-14 | UFC 198: Werdum vs. Miocic | Welterweight | Bryan Barberena def. Warlley Alves | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2016-01-30 | UFC on Fox: Johnson vs. Bader | Welterweight | Bryan Barberena def. Sage Northcutt | Submission (arm-triangle choke) | 2 | 3:06 |
| 2015-04-25 | UFC 186: Johnson vs. Horiguchi | Lightweight | Chad Laprise def. Bryan Barberena | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2014-12-13 | UFC on Fox: dos Santos vs. Miocic | Lightweight | Bryan Barberena def. Joe Ellenberger | TKO (elbows and punches) | 3 | 3:24 |