| 2026-10-31 | UFC Fight Night: Moicano vs. Nolan | Welterweight | Jacobe Smith def. Randy Brown | Decision (unanimous) (30–26, 30–26, 30–26) | 3 | 5:00 |
| 2026-04-11 | UFC 327: Procházka vs. Ulberg | Welterweight | Kevin Holland def. Randy Brown | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2025-11-08 | UFC Fight Night: Bonfim vs. Brown | Welterweight | Gabriel Bonfim def. Randy Brown | TKO (knee) | 2 | 1:40 |
| 2025-04-26 | UFC on ESPN: Machado Garry vs. Prates | Welterweight | Randy Brown def. Nicolas Dalby | KO (punch) | 2 | 1:39 |
| 2024-12-07 | UFC 310: Pantoja vs. Asakura | Catchweight | Bryan Battle def. Randy Brown | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2024-06-01 | UFC 302: Makhachev vs. Poirier | Welterweight | Randy Brown def. Elizeu Zaleski dos Santos | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2024-02-03 | UFC Fight Night: Dolidze vs. Imavov | Welterweight | Randy Brown def. Muslim Salikhov | KO (punches) | 1 | 3:17 |
| 2023-06-24 | UFC on ABC: Emmett vs. Topuria | Welterweight | Randy Brown def. Wellington Turman | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2023-02-12 | UFC 284: Makhachev vs. Volkanovski | Welterweight | Jack Della Maddalena def. Randy Brown | Submission (rear-naked choke) | 1 | 2:13 |
| 2022-10-01 | UFC Fight Night: Dern vs. Yan | Welterweight | Randy Brown def. Francisco Trinaldo | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2022-05-07 | UFC 274: Oliveira vs. Gaethje | Welterweight | Randy Brown def. Khaos Williams | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2021-10-09 | UFC Fight Night: Dern vs. Rodriguez | Catchweight | Randy Brown def. Jared Gooden | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2021-04-24 | UFC 261: Usman vs. Masvidal 2 | Welterweight | Randy Brown def. Alex Oliveira | Submission (rear-naked choke) | 1 | 2:50 |
| 2020-08-01 | UFC Fight Night: Brunson vs. Shahbazyan | Welterweight | Vicente Luque def. Randy Brown | KO (knee and punches) | 2 | 4:56 |
| 2019-11-16 | UFC Fight Night: Błachowicz vs. Jacaré | Welterweight | Randy Brown def. Warlley Alves | Submission (triangle choke) | 2 | 1:22 |
| 2019-06-22 | UFC Fight Night: Moicano vs. The Korean Zombie | Welterweight | Randy Brown def. Bryan Barberena | TKO (punches) | 3 | 2:54 |
| 2018-07-14 | UFC Fight Night: dos Santos vs. Ivanov | Welterweight | Niko Price def. Randy Brown | KO (punches) | 2 | 1:09 |
| 2017-11-04 | UFC 217: Bisping vs. St-Pierre | Welterweight | Randy Brown def. Mickey Gall | Decision (unanimous) (29–28, 29–28, 29–27) | 3 | 5:00 |
| 2017-02-11 | UFC 208: Holm vs. de Randamie | Welterweight | Belal Muhammad def. Randy Brown | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2016-12-09 | UFC Fight Night: Lewis vs. Abdurakhimov | Welterweight | Randy Brown def. Brian Camozzi | TKO (knee and punches) | 2 | 1:25 |
| 2016-09-17 | UFC Fight Night: Poirier vs. Johnson | Welterweight | Randy Brown def. Erick Montaño | Submission (guillotine choke) | 3 | 0:18 |
| 2016-04-16 | UFC on Fox: Teixeira vs. Evans | Welterweight | Michael Graves def. Randy Brown | Submission (rear-naked choke) | 2 | 2:31 |
| 2016-01-30 | UFC on Fox: Johnson vs. Bader | Welterweight | Randy Brown def. Matt Dwyer | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |