| 2025-04-26 | UFC on ESPN: Machado Garry vs. Prates | Light Heavyweight | Zhang Mingyang def. Anthony Smith | TKO (elbows) | 1 | 4:03 |
| 2024-12-07 | UFC 310: Pantoja vs. Asakura | Light Heavyweight | Dominick Reyes def. Anthony Smith | TKO (elbows and punches) | 2 | 4:46 |
| 2024-06-29 | UFC 303: Pereira vs. Procházka 2 | Light Heavyweight | Roman Dolidze def. Anthony Smith | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2024-05-04 | UFC 301: Pantoja vs. Erceg | Light Heavyweight | Anthony Smith def. Vitor Petrino | Submission (guillotine choke) | 1 | 2:00 |
| 2023-12-09 | UFC Fight Night: Song vs. Gutiérrez | Light Heavyweight | Khalil Rountree Jr. def. Anthony Smith | TKO (punches) | 3 | 0:56 |
| 2023-08-26 | UFC Fight Night: Holloway vs. The Korean Zombie | Light Heavyweight | Anthony Smith def. Ryan Spann | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2023-05-13 | UFC on ABC: Rozenstruik vs. Almeida | Light Heavyweight | Johnny Walker def. Anthony Smith | Decision (unanimous) (29–28, 30–27, 30–27) | 3 | 5:00 |
| 2022-07-30 | UFC 277: Peña vs. Nunes 2 | Light Heavyweight | Magomed Ankalaev def. Anthony Smith | TKO (punches) | 2 | 3:09 |
| 2021-09-18 | UFC Fight Night: Smith vs. Spann | Light Heavyweight | Anthony Smith def. Ryan Spann | Submission (rear-naked choke) | 1 | 3:47 |
| 2021-04-24 | UFC 261: Usman vs. Masvidal 2 | Light Heavyweight | Anthony Smith def. Jimmy Crute | TKO (doctor stoppage) | 1 | 5:00 |
| 2020-11-28 | UFC on ESPN: Smith vs. Clark | Light Heavyweight | Anthony Smith def. Devin Clark | Submission (triangle choke) | 1 | 2:34 |
| 2020-08-29 | UFC Fight Night: Smith vs. Rakić | Light Heavyweight | Aleksandar Rakić def. Anthony Smith | Decision (unanimous) (30–26, 30–27, 30–27) | 3 | 5:00 |
| 2020-05-13 | UFC Fight Night: Smith vs. Teixeira | Light Heavyweight | Glover Teixeira def. Anthony Smith | TKO (punches) | 5 | 1:04 |
| 2019-06-01 | UFC Fight Night: Gustafsson vs. Smith | Light Heavyweight | Anthony Smith def. Alexander Gustafsson | Submission (rear-naked choke) | 4 | 2:38 |
| 2019-03-02 | UFC 235: Jones vs. Smith | Light Heavyweight | Jon Jones def. Anthony Smith title | Decision (unanimous) (48–44, 48–44, 48–44) | 5 | 5:00 |
| 2018-10-27 | UFC Fight Night: Volkan vs. Smith | Light Heavyweight | Anthony Smith def. Volkan Oezdemir | Submission (rear-naked choke) | 3 | 4:26 |
| 2018-07-22 | UFC Fight Night: Shogun vs. Smith | Light Heavyweight | Anthony Smith def. Maurício Rua | KO (elbow and punches) | 1 | 1:29 |
| 2018-06-09 | UFC 225: Whittaker vs. Romero 2 | Light Heavyweight | Anthony Smith def. Rashad Evans | KO (knee) | 1 | 0:53 |
| 2018-02-03 | UFC Fight Night: Machida vs. Anders | Middleweight | Thiago Santos def. Anthony Smith | TKO (body kick and punches) | 2 | 1:03 |
| 2017-09-16 | UFC Fight Night: Rockhold vs. Branch | Middleweight | Anthony Smith def. Hector Lombard | TKO (punches) | 3 | 2:33 |
| 2017-04-15 | UFC on Fox: Johnson vs. Reis | Middleweight | Anthony Smith def. Andrew Sanchez | KO (head kick and punches) | 3 | 3:52 |
| 2016-12-03 | The Ultimate Fighter: Tournament of Champions Finale | Middleweight | Anthony Smith def. Elvis Mutapčić | TKO (elbow and punches) | 2 | 3:27 |
| 2016-07-08 | The Ultimate Fighter: Team Joanna vs. Team Cláudia Finale | Middleweight | Cezar Ferreira def. Anthony Smith | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2016-02-21 | UFC Fight Night: Cowboy vs. Cowboy | Middleweight | Anthony Smith def. Leonardo Augusto Guimarães | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2013-06-08 | UFC on Fuel TV: Nogueira vs. Werdum | Middleweight | Antônio Braga Neto def. Anthony Smith | Submission (kneebar) | 1 | 1:52 |