| 2026-10-24 | UFC 333: Volkanovski vs. Evloev | Light Heavyweight | Dominick Reyes def. Azamat Murzakanov | TKO (head kick and punches) | 1 | 2:40 |
| 2026-04-11 | UFC 327: Procházka vs. Ulberg | Light Heavyweight | Dominick Reyes def. Johnny Walker | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2025-09-28 | UFC Fight Night: Ulberg vs. Reyes | Light Heavyweight | Carlos Ulberg def. Dominick Reyes | KO (punches) | 1 | 4:27 |
| 2025-04-12 | UFC 314: Volkanovski vs. Lopes | Light Heavyweight | Dominick Reyes def. Nikita Krylov | KO (punch) | 1 | 2:24 |
| 2024-12-07 | UFC 310: Pantoja vs. Asakura | Light Heavyweight | Dominick Reyes def. Anthony Smith | TKO (elbows and punches) | 2 | 4:46 |
| 2024-06-08 | UFC on ESPN: Cannonier vs. Imavov | Light Heavyweight | Dominick Reyes def. Dustin Jacoby | KO (punches) | 1 | 2:00 |
| 2022-11-12 | UFC 281: Adesanya vs. Pereira | Catchweight | Ryan Spann def. Dominick Reyes | KO (punches) | 1 | 1:20 |
| 2021-05-01 | UFC on ESPN: Reyes vs. Procházka | Light Heavyweight | Jiří Procházka def. Dominick Reyes | KO (spinning back elbow) | 2 | 4:29 |
| 2020-09-27 | UFC 253: Adesanya vs. Costa | Light Heavyweight | Jan Błachowicz def. Dominick Reyes title | TKO (punches) | 2 | 4:36 |
| 2020-02-08 | UFC 247: Jones vs. Reyes | Light Heavyweight | Jon Jones def. Dominick Reyes title | Decision (unanimous) (48–47, 48–47, 49–46) | 5 | 5:00 |
| 2019-10-18 | UFC on ESPN: Reyes vs. Weidman | Light Heavyweight | Dominick Reyes def. Chris Weidman | KO (punches) | 1 | 1:43 |
| 2019-03-16 | UFC Fight Night: Till vs. Masvidal | Light Heavyweight | Dominick Reyes def. Volkan Oezdemir | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2018-10-06 | UFC 229: Khabib vs. McGregor | Light Heavyweight | Dominick Reyes def. Ovince Saint Preux | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2018-05-19 | UFC Fight Night: Maia vs. Usman | Light Heavyweight | Dominick Reyes def. Jared Cannonier | TKO (punches) | 1 | 2:55 |
| 2017-12-02 | UFC 218: Holloway vs. Aldo 2 | Light Heavyweight | Dominick Reyes def. Jeremy Kimball | Submission (rear-naked choke) | 1 | 3:39 |
| 2017-06-25 | UFC Fight Night: Chiesa vs. Lee | Light Heavyweight | Dominick Reyes def. Joachim Christensen | TKO (punches) | 1 | 0:29 |