| 2021-06-26 | UFC Fight Night: Gane vs. Volkov | Lightweight | Damir Hadžović def. Yancy Medeiros | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2020-02-15 | UFC Fight Night: Anderson vs. Błachowicz 2 | Lightweight | Lando Vannata def. Yancy Medeiros | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2019-01-19 | UFC Fight Night: Cejudo vs. Dillashaw | Lightweight | Gregor Gillespie def. Yancy Medeiros | TKO (punches) | 2 | 4:59 |
| 2018-02-18 | UFC Fight Night: Cowboy vs. Medeiros | Welterweight | Donald Cerrone def. Yancy Medeiros | TKO (punches) | 1 | 4:58 |
| 2017-12-02 | UFC 218: Holloway vs. Aldo 2 | Welterweight | Yancy Medeiros def. Alex Oliveira | TKO (punches) | 3 | 2:02 |
| 2017-06-03 | UFC 212: Aldo vs. Holloway | Welterweight | Yancy Medeiros def. Erick Silva | TKO (punches) | 2 | 2:01 |
| 2016-09-10 | UFC 203: Miocic vs. Overeem | Welterweight | Yancy Medeiros def. Sean Spencer | Submission (rear-naked choke) | 2 | 0:49 |
| 2016-05-14 | UFC 198: Werdum vs. Miocic | Lightweight | Francisco Trinaldo def. Yancy Medeiros | Decision (unanimous) (29–26, 30–27, 30–26) | 3 | 5:00 |
| 2015-12-12 | UFC 194: Aldo vs. McGregor | Lightweight | Yancy Medeiros def. John Makdessi | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2015-06-06 | UFC Fight Night: Boetsch vs. Henderson | Catchweight | Dustin Poirier def. Yancy Medeiros | TKO (body kick and punches) | 1 | 2:38 |
| 2014-12-12 | The Ultimate Fighter: A Champion Will Be Crowned Finale | Lightweight | Yancy Medeiros def. Joe Proctor | Submission (guillotine choke) | 1 | 4:37 |
| 2014-08-30 | UFC 177: Dillashaw vs. Soto | Lightweight | Yancy Medeiros def. Damon Jackson | Submission (reverse bulldog choke) | 2 | 1:54 |
| 2014-04-26 | UFC 172: Jones vs. Teixeira | Lightweight | Jim Miller def. Yancy Medeiros | Technical Submission (guillotine choke) | 1 | 3:18 |
| 2013-11-06 | UFC: Fight for the Troops 3 | Lightweight | Yancy Medeiros vs. Yves Edwards | No contest (overturned; original: No Contest (overturned)) | 1 | 2:47 |
| 2013-04-27 | UFC 159: Jones vs. Sonnen | Lightweight | Rustam Khabilov def. Yancy Medeiros | TKO (thumb injury) | 1 | 2:32 |