| 2024-12-07 | UFC 310: Pantoja vs. Asakura | Catchweight | Eryk Anders def. Chris Weidman | TKO (punches) | 2 | 4:51 |
| 2024-03-30 | UFC on ESPN: Blanchfield vs. Fiorot | Middleweight | Chris Weidman def. Bruno Silva | Technical Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 2:18 |
| 2023-08-19 | UFC 292: Sterling vs. O'Malley | Middleweight | Brad Tavares def. Chris Weidman | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2021-04-24 | UFC 261: Usman vs. Masvidal 2 | Middleweight | Uriah Hall def. Chris Weidman | TKO (leg injury) | 1 | 0:17 |
| 2020-08-08 | UFC Fight Night: Lewis vs. Oleinik | Middleweight | Chris Weidman def. Omari Akhmedov | Decision (unanimous) (29–27, 29–27, 29–28) | 3 | 5:00 |
| 2019-10-18 | UFC on ESPN: Reyes vs. Weidman | Light Heavyweight | Dominick Reyes def. Chris Weidman | KO (punches) | 1 | 1:43 |
| 2018-11-03 | UFC 230: Cormier vs. Lewis | Middleweight | Ronaldo Souza def. Chris Weidman | KO (punches) | 3 | 2:46 |
| 2017-07-22 | UFC on Fox: Weidman vs. Gastelum | Middleweight | Chris Weidman def. Kelvin Gastelum | Submission (arm-triangle choke) | 3 | 3:45 |
| 2017-04-08 | UFC 210: Cormier vs. Johnson 2 | Middleweight | Gegard Mousasi def. Chris Weidman | TKO (knees) | 2 | 3:13 |
| 2016-11-12 | UFC 205: Alvarez vs. McGregor | Middleweight | Yoel Romero def. Chris Weidman | KO (flying knee and punches) | 3 | 0:24 |
| 2015-12-12 | UFC 194: Aldo vs. McGregor | Middleweight | Luke Rockhold def. Chris Weidman title | TKO (punches) | 4 | 3:12 |
| 2015-05-23 | UFC 187: Johnson vs. Cormier | Middleweight | Chris Weidman def. Vitor Belfort title | TKO (punches) | 1 | 2:53 |
| 2014-07-05 | UFC 175: Weidman vs. Machida | Middleweight | Chris Weidman def. Lyoto Machida title | Decision (unanimous) (49–45, 48–47, 49–46) | 5 | 5:00 |
| 2013-12-28 | UFC 168: Weidman vs. Silva 2 | Middleweight | Chris Weidman def. Anderson Silva title | TKO (leg injury) | 2 | 1:16 |
| 2013-07-06 | UFC 162: Silva vs. Weidman | Middleweight | Chris Weidman def. Anderson Silva title | KO (punches) | 2 | 1:18 |
| 2012-07-11 | UFC on Fuel TV: Muñoz vs. Weidman | Middleweight | Chris Weidman def. Mark Muñoz | KO (elbow and punches) | 2 | 1:37 |
| 2012-01-28 | UFC on Fox: Evans vs. Davis | Middleweight | Chris Weidman def. Demian Maia | Decision (unanimous) (29–28, 30–27, 29–28) | 3 | 5:00 |
| 2011-11-19 | UFC 139: Shogun vs. Henderson | Middleweight | Chris Weidman def. Tom Lawlor | Technical Submission (D'Arce choke) | 1 | 2:07 |
| 2011-06-11 | UFC 131: dos Santos vs. Carwin | Middleweight | Chris Weidman def. Jesse Bongfeldt | Submission (guillotine choke) | 1 | 4:54 |
| 2011-03-03 | UFC Live: Sanchez vs. Kampmann | Middleweight | Chris Weidman def. Alessio Sakara | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |