| 2024-11-02 | UFC Fight Night: Moreno vs. Albazi | Welterweight | Mike Malott def. Trevin Giles | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2024-02-10 | UFC Fight Night: Hermansson vs. Pyfer | Welterweight | Carlos Prates def. Trevin Giles | KO (punch) | 2 | 4:03 |
| 2023-07-29 | UFC 291: Poirier vs. Gaethje 2 | Welterweight | Gabriel Bonfim def. Trevin Giles | Submission (guillotine choke) | 1 | 1:13 |
| 2023-03-25 | UFC on ESPN: Vera vs. Sandhagen | Welterweight | Trevin Giles def. Preston Parsons | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2022-09-17 | UFC Fight Night: Sandhagen vs. Song | Welterweight | Trevin Giles def. Louis Cosce | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2022-01-22 | UFC 270: Ngannou vs. Gane | Welterweight | Michael Morales def. Trevin Giles | TKO (punches) | 1 | 4:06 |
| 2021-07-10 | UFC 264: Poirier vs. McGregor 3 | Middleweight | Dricus du Plessis def. Trevin Giles | KO (punches) | 2 | 1:41 |
| 2021-03-20 | UFC on ESPN: Brunson vs. Holland | Middleweight | Trevin Giles def. Roman Dolidze | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2020-11-07 | UFC on ESPN: Santos vs. Teixeira | Middleweight | Trevin Giles def. Bevon Lewis | TKO (punches) | 3 | 1:26 |
| 2020-02-08 | UFC 247: Jones vs. Reyes | Middleweight | Trevin Giles def. James Krause | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2019-08-03 | UFC on ESPN: Covington vs. Lawler | Middleweight | Gerald Meerschaert def. Trevin Giles | Technical Submission (guillotine choke) | 3 | 1:49 |
| 2019-05-18 | UFC Fight Night: dos Anjos vs. Lee | Middleweight | Zak Cummings def. Trevin Giles | Submission (guillotine choke) | 3 | 4:01 |
| 2017-12-09 | UFC Fight Night: Swanson vs. Ortega | Middleweight | Trevin Giles def. Antônio Braga Neto | TKO (punches) | 3 | 2:27 |
| 2017-07-08 | UFC 213: Romero vs. Whittaker | Light Heavyweight | Trevin Giles def. James Bochnovic | KO (punches) | 2 | 2:54 |