| 2026-05-09 | UFC 328: Chimaev vs. Strickland | Middleweight | Sean Strickland def. Khamzat Chimaev title | Decision (split) (47–48, 48–47, 48–47) | 5 | 5:00 |
| 2026-02-21 | UFC Fight Night: Strickland vs. Hernandez | Middleweight | Sean Strickland def. Anthony Hernandez | TKO (punches) | 3 | 2:23 |
| 2025-02-08 | UFC 312: du Plessis vs. Strickland 2 | Middleweight | Dricus du Plessis def. Sean Strickland title | Decision (unanimous) (50–45, 50–45, 49–46) | 5 | 5:00 |
| 2024-06-01 | UFC 302: Makhachev vs. Poirier | Middleweight | Sean Strickland def. Paulo Costa | Decision (split) (46–49, 50–45, 49–46) | 5 | 5:00 |
| 2024-01-20 | UFC 297: Strickland vs. du Plessis | Middleweight | Dricus du Plessis def. Sean Strickland title | Decision (split) (47–48, 48–47, 48–47) | 5 | 5:00 |
| 2023-09-10 | UFC 293: Adesanya vs. Strickland | Middleweight | Sean Strickland def. Israel Adesanya title | Decision (unanimous) (49–46, 49–46, 49–46) | 5 | 5:00 |
| 2023-07-01 | UFC on ESPN: Strickland vs. Magomedov | Middleweight | Sean Strickland def. Abusupiyan Magomedov | TKO (punches) | 2 | 4:20 |
| 2023-01-14 | UFC Fight Night: Strickland vs. Imavov | Light Heavyweight | Sean Strickland def. Nassourdine Imavov | Decision (unanimous) (49–46, 49–46, 48–47) | 5 | 5:00 |
| 2022-12-17 | UFC Fight Night: Cannonier vs. Strickland | Middleweight | Jared Cannonier def. Sean Strickland | Decision (split) (49–46, 46–49, 49–46) | 5 | 5:00 |
| 2022-07-02 | UFC 276: Adesanya vs. Cannonier | Middleweight | Alex Pereira def. Sean Strickland | KO (punches) | 1 | 2:36 |
| 2022-02-05 | UFC Fight Night: Hermansson vs. Strickland | Middleweight | Sean Strickland def. Jack Hermansson | Decision (split) (49–46, 47–48, 49–46) | 5 | 5:00 |
| 2021-07-31 | UFC on ESPN: Hall vs. Strickland | Middleweight | Sean Strickland def. Uriah Hall | Decision (unanimous) (50–44, 50–45, 49–46) | 5 | 5:00 |
| 2021-05-01 | UFC on ESPN: Reyes vs. Procházka | Middleweight | Sean Strickland def. Krzysztof Jotko | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2020-11-14 | UFC Fight Night: Felder vs. dos Anjos | Catchweight | Sean Strickland def. Brendan Allen | TKO (punches) | 2 | 1:32 |
| 2020-10-31 | UFC Fight Night: Hall vs. Silva | Catchweight | Sean Strickland def. Jack Marshman | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2018-10-27 | UFC Fight Night: Volkan vs. Smith | Welterweight | Sean Strickland def. Nordine Taleb | TKO (punches) | 2 | 3:10 |
| 2018-05-12 | UFC 224: Nunes vs. Pennington | Welterweight | Elizeu Zaleski dos Santos def. Sean Strickland | KO (spinning wheel kick and punches) | 1 | 3:40 |
| 2017-11-11 | UFC Fight Night: Poirier vs. Pettis | Welterweight | Sean Strickland def. Court McGee | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2017-04-08 | UFC 210: Cormier vs. Johnson 2 | Welterweight | Kamaru Usman def. Sean Strickland | Decision (unanimous) (30–27, 30–26, 30–26) | 3 | 5:00 |
| 2016-06-04 | UFC 199: Rockhold vs. Bisping 2 | Welterweight | Sean Strickland def. Tom Breese | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2016-02-21 | UFC Fight Night: Cowboy vs. Cowboy | Welterweight | Sean Strickland def. Alex Garcia | TKO (punches) | 3 | 4:25 |
| 2015-07-15 | UFC Fight Night: Mir vs. Duffee | Welterweight | Sean Strickland def. Igor Araújo | Decision (unanimous) (30–27, 30–27, 30–26) | 3 | 5:00 |
| 2015-02-22 | UFC Fight Night: Bigfoot vs. Mir | Welterweight | Santiago Ponzinibbio def. Sean Strickland | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2014-05-31 | UFC Fight Night: Muñoz vs. Mousasi | Middleweight | Sean Strickland def. Luke Barnatt | Decision (split) (28–29, 30–27, 29–28) | 3 | 5:00 |
| 2014-03-15 | UFC 171: Hendricks vs. Lawler | Middleweight | Sean Strickland def. Bubba McDaniel | Submission (rear-naked choke) | 1 | 4:33 |