| 2026-06-14 | UFC Freedom 250 | Lightweight | Justin Gaethje def. Ilia Topuria title | TKO (corner stoppage) | 4 | 5:00 |
| 2026-01-24 | UFC 324: Gaethje vs. Pimblett | Lightweight | Justin Gaethje def. Paddy Pimblett title | Decision (unanimous) (48–47, 49–46, 49–46) | 5 | 5:00 |
| 2025-03-08 | UFC 313: Pereira vs. Ankalaev | Lightweight | Justin Gaethje def. Rafael Fiziev | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2024-04-13 | UFC 300: Pereira vs. Hill | Lightweight | Max Holloway def. Justin Gaethje title | KO (punch) | 5 | 4:59 |
| 2023-07-29 | UFC 291: Poirier vs. Gaethje 2 | Lightweight | Justin Gaethje def. Dustin Poirier | KO (head kick) | 2 | 1:00 |
| 2023-03-18 | UFC 286: Edwards vs. Usman 3 | Lightweight | Justin Gaethje def. Rafael Fiziev | Decision (majority) (29–28, 29–28, 28–28) | 3 | 5:00 |
| 2022-05-07 | UFC 274: Oliveira vs. Gaethje | Lightweight | Charles Oliveira def. Justin Gaethje title | Submission (rear-naked choke) | 1 | 3:22 |
| 2021-11-06 | UFC 268: Usman vs. Covington 2 | Lightweight | Justin Gaethje def. Michael Chandler | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2020-10-24 | UFC 254: Khabib vs. Gaethje | Lightweight | Khabib Nurmagomedov def. Justin Gaethje title | Technical Submission (triangle choke) | 2 | 1:34 |
| 2020-05-09 | UFC 249: Ferguson vs. Gaethje | Lightweight | Justin Gaethje def. Tony Ferguson title | TKO (punch) | 5 | 3:39 |
| 2019-09-14 | UFC Fight Night: Cowboy vs. Gaethje | Lightweight | Justin Gaethje def. Donald Cerrone | TKO (punches) | 1 | 4:18 |
| 2019-03-30 | UFC on ESPN: Barboza vs. Gaethje | Lightweight | Justin Gaethje def. Edson Barboza | KO (punch) | 1 | 2:30 |
| 2018-08-25 | UFC Fight Night: Gaethje vs. Vick | Lightweight | Justin Gaethje def. James Vick | KO (punch) | 1 | 1:27 |
| 2018-04-14 | UFC on Fox: Poirier vs. Gaethje | Lightweight | Dustin Poirier def. Justin Gaethje | TKO (punches) | 4 | 0:33 |
| 2017-12-02 | UFC 218: Holloway vs. Aldo 2 | Lightweight | Eddie Alvarez def. Justin Gaethje | KO (knee) | 3 | 3:59 |
| 2017-07-07 | The Ultimate Fighter: Redemption Finale | Lightweight | Justin Gaethje def. Michael Johnson | TKO (punches and knees) | 2 | 4:48 |