| 2026-06-14 | UFC Freedom 250 | Lightweight | Justin Gaethje def. Ilia Topuria title | TKO (corner stoppage) | 4 | 5:00 |
| 2025-06-28 | UFC 317: Topuria vs. Oliveira | Lightweight | Ilia Topuria def. Charles Oliveira title | KO (punches) | 1 | 2:27 |
| 2024-10-26 | UFC 308: Topuria vs. Holloway | Featherweight | Ilia Topuria def. Max Holloway title | KO (punches) | 3 | 1:34 |
| 2024-02-17 | UFC 298: Volkanovski vs. Topuria | Featherweight | Ilia Topuria def. Alexander Volkanovski title | KO (punch) | 2 | 3:32 |
| 2023-06-24 | UFC on ABC: Emmett vs. Topuria | Featherweight | Ilia Topuria def. Josh Emmett | Decision (unanimous) (50–44, 50–42, 49–45) | 5 | 5:00 |
| 2022-12-10 | UFC 282: Błachowicz vs. Ankalaev | Featherweight | Ilia Topuria def. Bryce Mitchell | Submission (arm-triangle choke) | 2 | 3:10 |
| 2022-03-19 | UFC Fight Night: Volkov vs. Aspinall | Lightweight | Ilia Topuria def. Jai Herbert | KO (punches) | 2 | 1:07 |
| 2021-07-10 | UFC 264: Poirier vs. McGregor 3 | Featherweight | Ilia Topuria def. Ryan Hall | KO (punches) | 1 | 4:47 |
| 2020-12-05 | UFC on ESPN: Hermansson vs. Vettori | Featherweight | Ilia Topuria def. Damon Jackson | KO (punches) | 1 | 2:38 |
| 2020-10-11 | UFC Fight Night: Moraes vs. Sandhagen | Featherweight | Ilia Topuria def. Youssef Zalal | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |