| 2026-06-14 | UFC Freedom 250 | Heavyweight | Ciryl Gane def. Alex Pereira title | TKO (punches) | 2 | 1:27 |
| 2025-10-25 | UFC 321: Aspinall vs. Gane | Heavyweight | Tom Aspinall vs. Ciryl Gane title | NC (accidental eye poke) | 1 | 4:35 |
| 2024-12-07 | UFC 310: Pantoja vs. Asakura | Heavyweight | Ciryl Gane def. Alexander Volkov | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2023-09-02 | UFC Fight Night: Gane vs. Spivac | Heavyweight | Ciryl Gane def. Serghei Spivac | TKO (punches) | 2 | 3:44 |
| 2023-03-04 | UFC 285: Jones vs. Gane | Heavyweight | Jon Jones def. Ciryl Gane title | Submission (guillotine choke) | 1 | 2:04 |
| 2022-09-03 | UFC Fight Night: Gane vs. Tuivasa | Heavyweight | Ciryl Gane def. Tai Tuivasa | KO (punches) | 3 | 4:23 |
| 2022-01-22 | UFC 270: Ngannou vs. Gane | Heavyweight | Francis Ngannou def. Ciryl Gane title | Decision (unanimous) (48–47, 48–47, 49–46) | 5 | 5:00 |
| 2021-08-07 | UFC 265: Lewis vs. Gane | Heavyweight | Ciryl Gane def. Derrick Lewis title | TKO (punches) | 3 | 4:11 |
| 2021-06-26 | UFC Fight Night: Gane vs. Volkov | Heavyweight | Ciryl Gane def. Alexander Volkov | Decision (unanimous) (50–45, 50–45, 49–46) | 5 | 5:00 |
| 2021-02-27 | UFC Fight Night: Rozenstruik vs. Gane | Heavyweight | Ciryl Gane def. Jairzinho Rozenstruik | Decision (unanimous) (50–45, 50–45, 50–45) | 5 | 5:00 |
| 2020-12-12 | UFC 256: Figueiredo vs. Moreno | Heavyweight | Ciryl Gane def. Junior dos Santos | TKO (elbow) | 2 | 2:34 |
| 2019-12-21 | UFC Fight Night: Edgar vs. The Korean Zombie | Heavyweight | Ciryl Gane def. Tanner Boser | Decision (unanimous) (30–26, 30–26, 30–26) | 3 | 5:00 |
| 2019-10-26 | UFC Fight Night: Maia vs. Askren | Heavyweight | Ciryl Gane def. Don'Tale Mayes | Submission (heel hook) | 3 | 4:46 |
| 2019-08-10 | UFC Fight Night: Shevchenko vs. Carmouche 2 | Heavyweight | Ciryl Gane def. Raphael Pessoa | Submission (arm-triangle choke) | 1 | 4:12 |