| 2026-05-30 | UFC Fight Night: Song vs. Figueiredo | Welterweight | Jake Matthews def. Carlston Harris | Decision (unanimous) (30–25, 30–27, 30–27) | 3 | 5:00 |
| 2025-09-28 | UFC Fight Night: Ulberg vs. Reyes | Welterweight | Neil Magny def. Jake Matthews | Submission (brabo choke) | 3 | 3:08 |
| 2025-07-12 | UFC on ESPN: Lewis vs. Teixeira | Welterweight | Jake Matthews def. Chidi Njokuani | Submission (rear-naked choke) | 1 | 1:09 |
| 2025-02-08 | UFC 312: du Plessis vs. Strickland 2 | Welterweight | Jake Matthews def. Francisco Prado | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2024-06-01 | UFC 302: Makhachev vs. Poirier | Welterweight | Jake Matthews def. Philip Rowe | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2023-11-18 | UFC Fight Night: Allen vs. Craig | Welterweight | Michael Morales def. Jake Matthews | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2023-07-29 | UFC 291: Poirier vs. Gaethje 2 | Welterweight | Jake Matthews def. Darrius Flowers | Submission (rear-naked choke) | 2 | 2:37 |
| 2022-12-17 | UFC Fight Night: Cannonier vs. Strickland | Welterweight | Matthew Semelsberger def. Jake Matthews | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2022-06-12 | UFC 275: Teixeira vs. Procházka | Welterweight | Jake Matthews def. André Fialho | KO (punches) | 2 | 2:24 |
| 2021-03-06 | UFC 259: Błachowicz vs. Adesanya | Welterweight | Sean Brady def. Jake Matthews | Submission (arm-triangle choke) | 3 | 3:28 |
| 2020-09-27 | UFC 253: Adesanya vs. Costa | Welterweight | Jake Matthews def. Diego Sanchez | Decision (unanimous) (30–26, 30–26, 30–26) | 3 | 5:00 |
| 2020-02-23 | UFC Fight Night: Felder vs. Hooker | Welterweight | Jake Matthews def. Emil Weber Meek | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2019-10-05 | UFC 243: Whittaker vs. Adesanya | Welterweight | Jake Matthews def. Rostem Akman | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2018-12-02 | UFC Fight Night: dos Santos vs. Tuivasa | Welterweight | Anthony Rocco Martin def. Jake Matthews | Technical Submission (anaconda choke) | 3 | 1:19 |
| 2018-06-23 | UFC Fight Night: Cowboy vs. Edwards | Welterweight | Jake Matthews def. Shinsho Anzai | Technical Submission (rear-naked choke) | 1 | 3:44 |
| 2018-02-11 | UFC 221: Romero vs. Rockhold | Welterweight | Jake Matthews def. Li Jingliang | Decision (unanimous) (29–28, 30–26, 30–26) | 3 | 5:00 |
| 2017-11-19 | UFC Fight Night: Werdum vs. Tybura | Welterweight | Jake Matthews def. Bojan Veličković | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2016-11-27 | UFC Fight Night: Whittaker vs. Brunson | Lightweight | Andrew Holbrook def. Jake Matthews | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2016-07-08 | The Ultimate Fighter: Team Joanna vs. Team Cláudia Finale | Lightweight | Kevin Lee def. Jake Matthews | TKO (punches) | 1 | 4:06 |
| 2016-03-20 | UFC Fight Night: Hunt vs. Mir | Lightweight | Jake Matthews def. Johnny Case | Submission (rear-naked choke) | 3 | 4:45 |
| 2015-11-15 | UFC 193: Rousey vs. Holm | Lightweight | Jake Matthews def. Akbarh Arreola | TKO (doctor stoppage) | 2 | 5:00 |
| 2015-05-10 | UFC Fight Night: Miocic vs. Hunt | Lightweight | James Vick def. Jake Matthews | Submission (guillotine choke) | 1 | 4:53 |
| 2014-11-08 | UFC Fight Night: Rockhold vs. Bisping | Lightweight | Jake Matthews def. Vagner Rocha | Technical Submission (rear-naked choke) | 2 | 1:52 |
| 2014-06-28 | UFC Fight Night: Te Huna vs. Marquardt | Lightweight | Jake Matthews def. Dashon Johnson | Submission (triangle choke) | 3 | 3:16 |