| 2026-08-15 | UFC 330: Makhachev vs. Machado Garry | Welterweight | Islam Makhachev def. Ian Machado Garry title | Decision (unanimous) (49–46, 49–46, 48–47) | 5 | 5:00 |
| 2025-11-15 | UFC 322: Della Maddalena vs. Makhachev | Welterweight | Islam Makhachev def. Jack Della Maddalena title | Decision (unanimous) (50–45, 50–45, 50–45) | 5 | 5:00 |
| 2025-01-18 | UFC 311: Makhachev vs. Moicano | Lightweight | Islam Makhachev def. Renato Moicano title | Submission (brabo choke) | 1 | 4:05 |
| 2024-06-01 | UFC 302: Makhachev vs. Poirier | Lightweight | Islam Makhachev def. Dustin Poirier title | Submission (brabo choke) | 5 | 2:42 |
| 2023-10-21 | UFC 294: Makhachev vs. Volkanovski 2 | Lightweight | Islam Makhachev def. Alexander Volkanovski title | KO (head kick and punches) | 1 | 3:06 |
| 2023-02-12 | UFC 284: Makhachev vs. Volkanovski | Lightweight | Islam Makhachev def. Alexander Volkanovski title | Decision (unanimous) (48–47, 48–47, 49–46) | 5 | 5:00 |
| 2022-10-22 | UFC 280: Oliveira vs. Makhachev | Lightweight | Islam Makhachev def. Charles Oliveira title | Submission (arm-triangle choke) | 2 | 3:16 |
| 2022-02-26 | UFC Fight Night: Makhachev vs. Green | Catchweight | Islam Makhachev def. Bobby Green | TKO (punches) | 1 | 3:23 |
| 2021-10-30 | UFC 267: Błachowicz vs. Teixeira | Lightweight | Islam Makhachev def. Dan Hooker | Submission (kimura) | 1 | 2:25 |
| 2021-07-17 | UFC on ESPN: Makhachev vs. Moisés | Lightweight | Islam Makhachev def. Thiago Moisés | Submission (rear-naked choke) | 4 | 2:38 |
| 2021-03-06 | UFC 259: Błachowicz vs. Adesanya | Lightweight | Islam Makhachev def. Drew Dober | Submission (arm-triangle choke) | 3 | 1:37 |
| 2019-09-07 | UFC 242: Khabib vs. Poirier | Lightweight | Islam Makhachev def. Davi Ramos | Decision (unanimous) (29–27, 30–26, 30–26) | 3 | 5:00 |
| 2019-04-20 | UFC Fight Night: Overeem vs. Oleinik | Lightweight | Islam Makhachev def. Arman Tsarukyan | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2018-07-28 | UFC on Fox: Alvarez vs. Poirier 2 | Lightweight | Islam Makhachev def. Kajan Johnson | Submission (armbar) | 1 | 4:43 |
| 2018-01-20 | UFC 220: Miocic vs. Ngannou | Lightweight | Islam Makhachev def. Gleison Tibau | KO (punch) | 1 | 0:57 |
| 2017-02-11 | UFC 208: Holm vs. de Randamie | Lightweight | Islam Makhachev def. Nik Lentz | Decision (unanimous) (30–25, 30–25, 30–27) | 3 | 5:00 |
| 2016-09-17 | UFC Fight Night: Poirier vs. Johnson | Lightweight | Islam Makhachev def. Chris Wade | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2015-10-03 | UFC 192: Cormier vs. Gustafsson | Lightweight | Adriano Martins def. Islam Makhachev | KO (punch) | 1 | 1:46 |
| 2015-05-23 | UFC 187: Johnson vs. Cormier | Lightweight | Islam Makhachev def. Leo Kuntz | Submission (rear-naked choke) | 2 | 2:38 |