| 2022-07-09 | UFC on ESPN: dos Anjos vs. Fiziev | Light Heavyweight | Kennedy Nzechukwu def. Karl Roberson | TKO (elbows) | 3 | 2:19 |
| 2022-03-12 | UFC Fight Night: Santos vs. Ankalaev | Light Heavyweight | Khalil Rountree Jr. def. Karl Roberson | TKO (body kick and punches) | 2 | 0:25 |
| 2021-04-24 | UFC 261: Usman vs. Masvidal 2 | Middleweight | Brendan Allen def. Karl Roberson | Submission (ankle lock) | 1 | 4:55 |
| 2020-06-13 | UFC on ESPN: Eye vs. Calvillo | Catchweight | Marvin Vettori def. Karl Roberson | Submission (rear-naked choke) | 1 | 4:17 |
| 2019-11-09 | UFC Fight Night: Magomedsharipov vs. Kattar | Middleweight | Karl Roberson def. Roman Kopylov | Submission (rear-naked choke) | 3 | 4:01 |
| 2019-07-13 | UFC Fight Night: de Randamie vs. Ladd | Middleweight | Karl Roberson def. Wellington Turman | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2019-01-19 | UFC Fight Night: Cejudo vs. Dillashaw | Light Heavyweight | Glover Teixeira def. Karl Roberson | Submission (arm-triangle choke) | 1 | 3:21 |
| 2018-11-03 | UFC 230: Cormier vs. Lewis | Middleweight | Karl Roberson def. Jack Marshman | Decision (unanimous) (30–26, 30–26, 30–27) | 3 | 5:00 |
| 2018-05-12 | UFC 224: Nunes vs. Pennington | Middleweight | Cezar Ferreira def. Karl Roberson | Technical Submission (arm-triangle choke) | 1 | 4:45 |
| 2017-11-11 | UFC Fight Night: Poirier vs. Pettis | Middleweight | Karl Roberson def. Darren Stewart | Submission (rear-naked choke) | 1 | 3:41 |