| 2021-08-28 | UFC on ESPN: Barboza vs. Chikadze | Light Heavyweight | Dustin Jacoby def. Darren Stewart | TKO (punches) | 1 | 3:04 |
| 2021-06-12 | UFC 263: Adesanya vs. Vettori 2 | Light Heavyweight | Eryk Anders def. Darren Stewart | Decision (unanimous) (29–28, 29–27, 29–27) | 3 | 5:00 |
| 2021-03-13 | UFC Fight Night: Edwards vs. Muhammad | Middleweight | Eryk Anders vs. Darren Stewart | No Contest (illegal knee) | 1 | 4:37 |
| 2020-09-19 | UFC Fight Night: Covington vs. Woodley | Middleweight | Kevin Holland def. Darren Stewart | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2020-08-08 | UFC Fight Night: Lewis vs. Oleinik | Middleweight | Darren Stewart def. Maki Pitolo | Submission (guillotine choke) | 1 | 3:41 |
| 2019-10-18 | UFC on ESPN: Reyes vs. Weidman | Catchweight | Darren Stewart def. Deron Winn | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2019-06-08 | UFC 238: Cejudo vs. Moraes | Middleweight | Darren Stewart def. Bevon Lewis | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2018-11-30 | The Ultimate Fighter: Heavy Hitters Finale | Middleweight | Edmen Shahbazyan def. Darren Stewart | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2018-09-08 | UFC 228: Woodley vs. Till | Middleweight | Darren Stewart def. Charles Byrd | TKO (elbow and punches) | 2 | 2:17 |
| 2018-05-27 | UFC Fight Night: Thompson vs. Till | Middleweight | Darren Stewart def. Eric Spicely | TKO (punches) | 2 | 1:47 |
| 2017-12-16 | UFC on Fox: Lawler vs. dos Anjos | Middleweight | Julian Marquez def. Darren Stewart | Submission (guillotine choke) | 2 | 2:42 |
| 2017-11-11 | UFC Fight Night: Poirier vs. Pettis | Middleweight | Karl Roberson def. Darren Stewart | Submission (rear-naked choke) | 1 | 3:41 |
| 2017-03-18 | UFC Fight Night: Manuwa vs. Anderson | Light Heavyweight | Francimar Barroso def. Darren Stewart | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2016-11-19 | UFC Fight Night: Bader vs. Nogueira 2 | Light Heavyweight | Darren Stewart vs. Francimar Barroso | No contest (overturned; original: No Contest (inadvertent headbutt)) | 1 | 1:34 |