| 2014-03-01 | The Ultimate Fighter China Finale: Kim vs. Hathaway | Welterweight | Kim Dong-hyun def. John Hathaway | KO (spinning elbow) | 3 | 1:02 |
| 2012-09-29 | UFC on Fuel TV: Struve vs. Miocic | Welterweight | John Hathaway def. John Maguire | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2012-05-05 | UFC on Fox: Diaz vs. Miller | Welterweight | John Hathaway def. Pascal Krauss | Decision (unanimous) (29–28, 30–27, 30–27) | 3 | 5:00 |
| 2011-03-26 | UFC Fight Night: Nogueira vs. Davis | Welterweight | John Hathaway def. Kris McCray | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2010-10-16 | UFC 120: Bisping vs. Akiyama | Welterweight | Mike Pyle def. John Hathaway | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2010-05-29 | UFC 114: Rampage vs. Evans | Welterweight | John Hathaway def. Diego Sanchez | Decision (unanimous) (30–27, 30–27, 30–26) | 3 | 5:00 |
| 2009-11-14 | UFC 105: Couture vs. Vera | Welterweight | John Hathaway def. Paul Taylor | Decision (unanimous) (30–27, 30–27, 30–26) | 3 | 5:00 |
| 2009-06-13 | UFC 99: The Comeback | Welterweight | John Hathaway def. Rick Story | Decision (unanimous) (29–28, 30–27, 29–28) | 3 | 5:00 |
| 2009-01-17 | UFC 93: Franklin vs. Henderson | Welterweight | John Hathaway def. Tom Egan | TKO (elbows) | 1 | 4:36 |