| 2015-12-19 | UFC on Fox: dos Anjos vs. Cowboy 2 | Lightweight | Nik Lentz def. Danny Castillo | Decision (split) (28–29, 29–28, 30–27) | 3 | 5:00 |
| 2015-07-25 | UFC on Fox: Dillashaw vs. Barão 2 | Lightweight | Jim Miller def. Danny Castillo | Decision (split) (28–29, 29–28, 30–27) | 3 | 5:00 |
| 2015-01-03 | UFC 182: Jones vs. Cormier | Lightweight | Paul Felder def. Danny Castillo | KO (spinning back fist) | 2 | 2:09 |
| 2014-08-30 | UFC 177: Dillashaw vs. Soto | Lightweight | Tony Ferguson def. Danny Castillo | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2014-04-26 | UFC 172: Jones vs. Teixeira | Lightweight | Danny Castillo def. Charlie Brenneman | KO (punch) | 2 | 0:21 |
| 2013-12-14 | UFC on Fox: Johnson vs. Benavidez 2 | Lightweight | Edson Barboza def. Danny Castillo | Decision (majority) (29–28, 29–28, 28–28) | 3 | 5:00 |
| 2013-07-27 | UFC on Fox: Johnson vs. Moraga | Catchweight | Danny Castillo def. Tim Means | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2013-02-16 | UFC on Fuel TV: Barão vs. McDonald | Lightweight | Danny Castillo def. Paul Sass | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2012-10-05 | UFC on FX: Browne vs. Bigfoot | Lightweight | Michael Johnson def. Danny Castillo | KO (punches) | 2 | 1:06 |
| 2012-05-05 | UFC on Fox: Diaz vs. Miller | Lightweight | Danny Castillo def. John Cholish | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2011-12-30 | UFC 141: Lesnar vs. Overeem | Lightweight | Danny Castillo def. Anthony Njokuani | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2011-11-19 | UFC 139: Shogun vs. Henderson | Catchweight | Danny Castillo def. Shamar Bailey | TKO (punches) | 1 | 4:52 |
| 2011-08-14 | UFC Live: Hardy vs. Lytle | Lightweight | Jacob Volkmann def. Danny Castillo | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2011-03-03 | UFC Live: Sanchez vs. Kampmann | Lightweight | Danny Castillo def. Joe Stevenson | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |