| 2023-04-08 | UFC 287: Pereira vs. Adesanya 2 | Women’s Strawweight | Lupita Godinez def. Cynthia Calvillo | Decision (split) (28–29, 29–28, 30–27) | 3 | 5:00 |
| 2022-08-13 | UFC on ESPN: Vera vs. Cruz | Women’s Flyweight | Nina Ansaroff def. Cynthia Calvillo | Decision (split) (28–29, 29–28, 30–27) | 3 | 5:00 |
| 2021-11-13 | UFC Fight Night: Holloway vs. Rodríguez | Women’s Flyweight | Andrea Lee def. Cynthia Calvillo | TKO (corner stoppage) | 2 | 5:00 |
| 2021-09-25 | UFC 266: Volkanovski vs. Ortega | Women’s Flyweight | Jéssica Andrade def. Cynthia Calvillo | TKO (punches) | 1 | 4:54 |
| 2020-11-21 | UFC 255: Figueiredo vs. Perez | Women’s Flyweight | Katlyn Chookagian def. Cynthia Calvillo | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2020-06-13 | UFC on ESPN: Eye vs. Calvillo | Catchweight | Cynthia Calvillo def. Jessica Eye | Decision (unanimous) (49–46, 49–46, 48–47) | 5 | 5:00 |
| 2019-12-07 | UFC on ESPN: Overeem vs. Rozenstruik | Catchweight | Marina Rodriguez vs. Cynthia Calvillo | Draw (majority) (29–28, 28–28, 28–28) | 3 | 5:00 |
| 2019-02-17 | UFC on ESPN: Ngannou vs. Velasquez | Women’s Strawweight | Cynthia Calvillo def. Cortney Casey | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2018-11-17 | UFC Fight Night: Magny vs. Ponzinibbio | Catchweight | Cynthia Calvillo def. Poliana Botelho | Submission (rear-naked choke) | 1 | 4:48 |
| 2017-12-30 | UFC 219: Cyborg vs. Holm | Women’s Strawweight | Carla Esparza def. Cynthia Calvillo | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2017-07-16 | UFC Fight Night: Nelson vs. Ponzinibbio | Catchweight | Cynthia Calvillo def. Joanne Calderwood | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2017-04-08 | UFC 210: Cormier vs. Johnson 2 | Women’s Strawweight | Cynthia Calvillo def. Pearl Gonzalez | Submission (rear-naked choke) | 3 | 3:45 |
| 2017-03-04 | UFC 209: Woodley vs. Thompson 2 | Women’s Strawweight | Cynthia Calvillo def. Amanda Cooper | Submission (rear-naked choke) | 1 | 3:19 |