| 2025-09-13 | UFC Fight Night: Lopes vs. Silva | Lightweight | Joaquim Silva def. Claudio Puelles | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2024-02-24 | UFC Fight Night: Moreno vs. Royval 2 | Lightweight | Farès Ziam def. Claudio Puelles | Decision (split) (28–29, 30–27, 29–28) | 3 | 5:00 |
| 2022-11-12 | UFC 281: Adesanya vs. Pereira | Lightweight | Dan Hooker def. Claudio Puelles | TKO (body kick) | 2 | 4:06 |
| 2022-04-23 | UFC Fight Night: Lemos vs. Andrade | Lightweight | Claudio Puelles def. Clay Guida | Submission (kneebar) | 1 | 3:01 |
| 2021-12-04 | UFC on ESPN: Font vs. Aldo | Lightweight | Claudio Puelles def. Chris Gruetzemacher | Submission (kneebar) | 3 | 3:25 |
| 2021-06-05 | UFC Fight Night: Rozenstruik vs. Sakai | Lightweight | Claudio Puelles def. Jordan Leavitt | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2019-09-21 | UFC Fight Night: Rodríguez vs. Stephens | Lightweight | Claudio Puelles def. Marcos Rosa Mariano | Decision (unanimous) (30–25, 30–25, 30–25) | 3 | 5:00 |
| 2018-05-19 | UFC Fight Night: Maia vs. Usman | Lightweight | Claudio Puelles def. Felipe Silva | Submission (kneebar) | 3 | 2:23 |
| 2016-11-05 | The Ultimate Fighter Latin America 3 Finale: dos Anjos vs. Ferguson | Lightweight | Martín Bravo def. Claudio Puelles | TKO (punches) | 2 | 1:55 |