| 2026-10-10 | UFC Fight Night: Allen vs. Duncan | Middleweight | Brendan Allen def. Christian Leroy Duncan | Submission (rear-naked choke) | 5 | 2:46 |
| 2026-07-18 | UFC Fight Night: du Plessis vs. Usman | Middleweight | Christian Leroy Duncan def. Jared Cannonier | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2026-03-21 | UFC Fight Night: Evloev vs. Murphy | Middleweight | Christian Leroy Duncan def. Roman Dolidze | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2025-11-08 | UFC Fight Night: Bonfim vs. Brown | Middleweight | Christian Leroy Duncan def. Marco Tulio | KO (spinning backfist and punches) | 2 | 3:20 |
| 2025-08-09 | UFC on ESPN: Dolidze vs. Hernandez | Middleweight | Christian Leroy Duncan def. Eryk Anders | TKO (spinning back elbow and punches) | 1 | 3:53 |
| 2025-03-22 | UFC Fight Night: Edwards vs. Brady | Middleweight | Christian Leroy Duncan def. Andrey Pulyaev | Decision (unanimous) (30–27, 30–27, 30–26) | 3 | 5:00 |
| 2024-07-27 | UFC 304: Edwards vs. Muhammad 2 | Middleweight | Gregory Rodrigues def. Christian Leroy Duncan | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2024-03-02 | UFC Fight Night: Rozenstruik vs. Gaziev | Middleweight | Christian Leroy Duncan def. Claudio Ribeiro | TKO (elbows and punches) | 2 | 1:57 |
| 2023-11-18 | UFC Fight Night: Allen vs. Craig | Middleweight | Christian Leroy Duncan def. Denis Tiuliulin | TKO (punches and elbows) | 2 | 4:24 |
| 2023-06-17 | UFC on ESPN: Vettori vs. Cannonier | Middleweight | Armen Petrosyan def. Christian Leroy Duncan | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2023-03-18 | UFC 286: Edwards vs. Usman 3 | Middleweight | Christian Leroy Duncan def. Duško Todorović | TKO (knee injury) | 1 | 1:52 |