| 2020-07-19 | UFC Fight Night: Figueiredo vs. Benavidez 2 | Lightweight | Joel Álvarez def. Joseph Duffy | Submission (guillotine choke) | 1 | 2:25 |
| 2019-03-16 | UFC Fight Night: Till vs. Masvidal | Lightweight | Marc Diakiese def. Joseph Duffy | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2017-11-04 | UFC 217: Bisping vs. St-Pierre | Lightweight | James Vick def. Joseph Duffy | TKO (punches) | 2 | 4:59 |
| 2017-03-18 | UFC Fight Night: Manuwa vs. Anderson | Lightweight | Joseph Duffy def. Reza Madadi | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2016-07-07 | UFC Fight Night: dos Anjos vs. Alvarez | Lightweight | Joseph Duffy def. Mitch Clarke | Submission (rear-naked choke) | 1 | 0:25 |
| 2016-01-02 | UFC 195: Lawler vs. Condit | Lightweight | Dustin Poirier def. Joseph Duffy | Decision (unanimous) (30–26, 30–27, 30–27) | 3 | 5:00 |
| 2015-07-18 | UFC Fight Night: Bisping vs. Leites | Lightweight | Joseph Duffy def. Ivan Jorge | Submission (triangle choke) | 1 | 3:05 |
| 2015-03-14 | UFC 185: Pettis vs. dos Anjos | Lightweight | Joseph Duffy def. Jake Lindsey | TKO (head kick and body punch) | 1 | 1:47 |