| 2024-10-19 | UFC Fight Night: Hernandez vs. Pereira | Women’s Strawweight | Elise Reed def. Jessica Penne | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2023-03-04 | UFC 285: Jones vs. Gane | Women’s Strawweight | Tabatha Ricci def. Jessica Penne | Submission (armbar) | 2 | 2:14 |
| 2022-07-16 | UFC on ABC: Ortega vs. Rodríguez | Women’s Strawweight | Emily Ducote def. Jessica Penne | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2021-08-07 | UFC 265: Lewis vs. Gane | Women’s Strawweight | Jessica Penne def. Karolina Kowalkiewicz | Submission (armbar) | 1 | 4:32 |
| 2021-04-17 | UFC on ESPN: Whittaker vs. Gastelum | Women’s Strawweight | Jessica Penne def. Lupita Godinez | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2017-04-22 | UFC Fight Night: Swanson vs. Lobov | Women’s Strawweight | Danielle Taylor def. Jessica Penne | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2016-06-04 | UFC 199: Rockhold vs. Bisping 2 | Women’s Strawweight | Jéssica Andrade def. Jessica Penne | TKO (punches) | 2 | 2:56 |
| 2015-06-20 | UFC Fight Night: Jędrzejczyk vs. Penne | Women’s Strawweight | Joanna Jędrzejczyk def. Jessica Penne title | TKO (punches and knee) | 3 | 4:22 |
| 2014-12-12 | The Ultimate Fighter: A Champion Will Be Crowned Finale | Women’s Strawweight | Jessica Penne def. Randa Markos | Decision (split) (28–29, 30–27, 29–28) | 3 | 5:00 |