| 2026-06-14 | UFC Freedom 250 | Featherweight | Diego Lopes def. Steve Garcia | KO (punches) | 2 | 2:42 |
| 2026-02-01 | UFC 325: Volkanovski vs. Lopes 2 | Featherweight | Alexander Volkanovski def. Diego Lopes title | Decision (unanimous) (49–46, 49–46, 50–45) | 5 | 5:00 |
| 2025-09-13 | UFC Fight Night: Lopes vs. Silva | Featherweight | Diego Lopes def. Jean Silva | TKO (spinning back elbow and punches) | 2 | 4:48 |
| 2025-04-12 | UFC 314: Volkanovski vs. Lopes | Featherweight | Alexander Volkanovski def. Diego Lopes title | Decision (unanimous) (48–47, 49–46, 49–46) | 5 | 5:00 |
| 2024-09-14 | UFC 306: O'Malley vs. Dvalishvili | Featherweight | Diego Lopes def. Brian Ortega | Decision (unanimous) (30–26, 30–27, 30–27) | 3 | 5:00 |
| 2024-06-29 | UFC 303: Pereira vs. Procházka 2 | Catchweight | Diego Lopes def. Dan Ige | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2024-04-13 | UFC 300: Pereira vs. Hill | Featherweight | Diego Lopes def. Sodiq Yusuff | TKO (punches) | 1 | 1:29 |
| 2023-11-11 | UFC 295: Procházka vs. Pereira | Featherweight | Diego Lopes def. Pat Sabatini | KO (punches) | 1 | 1:30 |
| 2023-08-05 | UFC on ESPN: Sandhagen vs. Font | Featherweight | Diego Lopes def. Gavin Tucker | Submission (armbar) | 1 | 1:38 |
| 2023-05-06 | UFC 288: Sterling vs. Cejudo | Featherweight | Movsar Evloev def. Diego Lopes | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |