| 2026-08-08 | UFC Fight Night: Gamrot vs. Salkilld | Featherweight | Yadier del Valle def. Darren Elkins | TKO (punch) | 1 | 0:35 |
| 2025-04-12 | UFC 314: Volkanovski vs. Lopes | Featherweight | Julian Erosa def. Darren Elkins | TKO (punches) | 1 | 4:15 |
| 2024-10-19 | UFC Fight Night: Hernandez vs. Pereira | Featherweight | Darren Elkins def. Daniel Pineda | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2023-10-14 | UFC Fight Night: Yusuff vs. Barboza | Featherweight | Darren Elkins def. T.J. Brown | Submission (rear-naked choke) | 3 | 2:23 |
| 2022-12-03 | UFC on ESPN: Thompson vs. Holland | Featherweight | Jonathan Pearce def. Darren Elkins | Decision (unanimous) (30–27, 30–27, 30–26) | 3 | 5:00 |
| 2022-04-30 | UFC on ESPN: Font vs. Vera | Featherweight | Darren Elkins def. Tristan Connelly | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2021-12-18 | UFC Fight Night: Lewis vs. Daukaus | Featherweight | Cub Swanson def. Darren Elkins | TKO (spinning wheel kick and punches) | 1 | 2:12 |
| 2021-07-24 | UFC on ESPN: Sandhagen vs. Dillashaw | Featherweight | Darren Elkins def. Darrick Minner | TKO (punches) | 2 | 3:48 |
| 2020-11-07 | UFC on ESPN: Santos vs. Teixeira | Featherweight | Darren Elkins def. Luiz Eduardo Garagorri | Submission (rear-naked choke) | 3 | 2:22 |
| 2020-05-16 | UFC on ESPN: Overeem vs. Harris | Featherweight | Nate Landwehr def. Darren Elkins | Decision (unanimous) (29–28, 30–27, 30–27) | 3 | 5:00 |
| 2019-07-13 | UFC Fight Night: de Randamie vs. Ladd | Featherweight | Ryan Hall def. Darren Elkins | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2018-11-17 | UFC Fight Night: Magny vs. Ponzinibbio | Featherweight | Ricardo Lamas def. Darren Elkins | TKO (elbows and punches) | 3 | 4:09 |
| 2018-07-14 | UFC Fight Night: dos Santos vs. Ivanov | Featherweight | Alexander Volkanovski def. Darren Elkins | Decision (unanimous) (30–27, 29–28, 29–28) | 3 | 5:00 |
| 2018-01-14 | UFC Fight Night: Stephens vs. Choi | Featherweight | Darren Elkins def. Michael Johnson | Submission (rear-naked choke) | 2 | 2:22 |
| 2017-07-22 | UFC on Fox: Weidman vs. Gastelum | Featherweight | Darren Elkins def. Dennis Bermudez | Decision (split) (29–28, 28–29, 29–28) | 3 | 5:00 |
| 2017-03-04 | UFC 209: Woodley vs. Thompson 2 | Featherweight | Darren Elkins def. Mirsad Bektić | KO (punches) | 3 | 3:19 |
| 2016-07-23 | UFC on Fox: Holm vs. Shevchenko | Featherweight | Darren Elkins def. Godofredo Pepey | Decision (unanimous) (29–27, 29–27, 30–26) | 3 | 5:00 |
| 2016-03-05 | UFC 196: McGregor vs. Diaz | Featherweight | Darren Elkins def. Chas Skelly | Decision (unanimous) (30–27, 29–27, 30–26) | 3 | 5:00 |
| 2015-10-24 | UFC Fight Night: Holohan vs. Smolka | Featherweight | Darren Elkins def. Robert Whiteford | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2014-12-20 | UFC Fight Night: Machida vs. Dollaway | Featherweight | Hacran Dias def. Darren Elkins | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2014-10-25 | UFC 179: Aldo vs. Mendes 2 | Featherweight | Darren Elkins def. Lucas Martins | Decision (split) (27–30, 30–27, 30–27) | 3 | 5:00 |
| 2014-01-25 | UFC on Fox: Henderson vs. Thomson | Featherweight | Jeremy Stephens def. Darren Elkins | Decision (unanimous) (29–28, 30–27, 30–27) | 3 | 5:00 |
| 2013-08-28 | UFC Fight Night: Condit vs. Kampmann 2 | Featherweight | Darren Elkins def. Hatsu Hioki | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2013-04-20 | UFC on Fox: Henderson vs. Melendez | Featherweight | Chad Mendes def. Darren Elkins | TKO (punches) | 1 | 1:08 |
| 2013-03-16 | UFC 158: St-Pierre vs. Diaz | Featherweight | Darren Elkins def. Antonio Carvalho | TKO (punches) | 1 | 3:06 |
| 2012-11-17 | UFC 154: St-Pierre vs. Condit | Featherweight | Darren Elkins def. Steven Siler | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2012-05-26 | UFC 146: dos Santos vs. Mir | Featherweight | Darren Elkins def. Diego Brandao | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2011-10-08 | UFC 136: Edgar vs. Maynard III | Featherweight | Darren Elkins def. Zhang Tiequan | Decision (unanimous) (30–27, 30–26, 30–27) | 3 | 5:00 |
| 2011-06-11 | UFC 131: dos Santos vs. Carwin | Featherweight | Darren Elkins def. Michihiro Omigawa | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2010-08-01 | UFC Live: Jones vs. Matyushenko | Lightweight | Charles Oliveira def. Darren Elkins | Submission (armbar) | 1 | 0:41 |
| 2010-03-21 | UFC Live: Vera vs. Jones | Lightweight | Darren Elkins def. Duane Ludwig | TKO (ankle injury) | 1 | 0:44 |