| 2016-10-08 | UFC 204: Bisping vs. Henderson 2 | Middleweight | Michael Bisping def. Dan Henderson title | Decision (unanimous) (48–47, 48–47, 49–46) | 5 | 5:00 |
| 2016-06-04 | UFC 199: Rockhold vs. Bisping 2 | Middleweight | Dan Henderson def. Hector Lombard | KO (elbow) | 2 | 1:27 |
| 2015-11-07 | UFC Fight Night: Belfort vs. Henderson 3 | Middleweight | Vitor Belfort def. Dan Henderson | KO (head kick and punches) | 1 | 2:07 |
| 2015-06-06 | UFC Fight Night: Boetsch vs. Henderson | Middleweight | Dan Henderson def. Tim Boetsch | KO (punches) | 1 | 0:28 |
| 2015-01-24 | UFC on Fox: Gustafsson vs. Johnson | Middleweight | Gegard Mousasi def. Dan Henderson | TKO (punches) | 1 | 1:10 |
| 2014-05-24 | UFC 173: Barão vs. Dillashaw | Light Heavyweight | Daniel Cormier def. Dan Henderson | Technical Submission (rear-naked choke) | 3 | 3:53 |
| 2014-03-23 | UFC Fight Night: Shogun vs. Henderson 2 | Light Heavyweight | Dan Henderson def. Maurício Rua | TKO (punches) | 3 | 1:31 |
| 2013-11-09 | UFC Fight Night: Belfort vs. Henderson 2 | Light Heavyweight | Vitor Belfort def. Dan Henderson | KO (head kick) | 1 | 1:17 |
| 2013-06-15 | UFC 161: Evans vs. Henderson | Light Heavyweight | Rashad Evans def. Dan Henderson | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2013-02-23 | UFC 157: Rousey vs. Carmouche | Light Heavyweight | Lyoto Machida def. Dan Henderson | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2011-11-19 | UFC 139: Shogun vs. Henderson | Light Heavyweight | Dan Henderson def. Maurício Rua | Decision (unanimous) (48–47, 48–47, 48–47) | 5 | 5:00 |
| 2009-07-11 | UFC 100 | Middleweight | Dan Henderson def. Michael Bisping | KO (punch) | 2 | 3:20 |
| 2009-01-17 | UFC 93: Franklin vs. Henderson | Light Heavyweight | Dan Henderson def. Rich Franklin | Decision (split) (29–28, 27–30, 29–28) | 3 | 5:00 |
| 2008-09-06 | UFC 88: Breakthrough | Middleweight | Dan Henderson def. Rousimar Palhares | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2008-03-01 | UFC 82: Pride of a Champion | Middleweight | Anderson Silva def. Dan Henderson title | Submission (rear-naked choke) | 2 | 4:52 |
| 2007-09-08 | UFC 75: Champion vs. Champion | Light Heavyweight | Quinton Jackson def. Dan Henderson | Decision (unanimous) (48–47, 49–46, 49–46) | 5 | 5:00 |
| 1998-05-15 | UFC 17: Redemption | Middleweight | Dan Henderson def. Carlos Newton | Decision (split) | | 15:00 |
| 1998-05-15 | UFC 17: Redemption | Middleweight | Dan Henderson def. Allan Góes | Decision (unanimous) | | 15:00 |