| 2019-09-21 | UFC Fight Night: Rodríguez vs. Stephens | Flyweight | Sergio Pettis def. Tyson Nam | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2018-12-15 | UFC on Fox: Lee vs. Iaquinta 2 | Bantamweight | Rob Font def. Sergio Pettis | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2018-10-06 | UFC 229: Khabib vs. McGregor | Flyweight | Jussier Formiga def. Sergio Pettis | Decision (unanimous) (30–26, 29–28, 29–28) | 3 | 5:00 |
| 2018-06-09 | UFC 225: Whittaker vs. Romero 2 | Flyweight | Sergio Pettis def. Joseph Benavidez | Decision (split) (28–29, 29–28, 30–27) | 3 | 5:00 |
| 2017-12-02 | UFC 218: Holloway vs. Aldo 2 | Flyweight | Henry Cejudo def. Sergio Pettis | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2017-08-05 | UFC Fight Night: Pettis vs. Moreno | Flyweight | Sergio Pettis def. Brandon Moreno | Decision (unanimous) (49–46, 48–46, 48–46) | 5 | 5:00 |
| 2017-01-15 | UFC Fight Night: Rodríguez vs. Penn | Flyweight | Sergio Pettis def. John Moraga | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2016-04-23 | UFC 197: Jones vs. Saint Preux | Flyweight | Sergio Pettis def. Chris Kelades | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2015-10-03 | UFC 192: Cormier vs. Gustafsson | Flyweight | Sergio Pettis def. Chris Cariaso | Decision (unanimous) (29–27, 29–27, 29–28) | 3 | 5:00 |
| 2015-03-14 | UFC 185: Pettis vs. dos Anjos | Flyweight | Ryan Benoit def. Sergio Pettis | TKO (punches) | 2 | 1:34 |
| 2014-12-06 | UFC 181: Hendricks vs. Lawler II | Bantamweight | Sergio Pettis def. Matt Hobar | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2014-06-07 | UFC Fight Night: Henderson vs. Khabilov | Bantamweight | Sergio Pettis def. Yaotzin Meza | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2014-01-25 | UFC on Fox: Henderson vs. Thomson | Bantamweight | Alex Caceres def. Sergio Pettis | Submission (rear-naked choke) | 3 | 4:39 |
| 2013-11-16 | UFC 167: St-Pierre vs. Hendricks | Bantamweight | Sergio Pettis def. Will Campuzano | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |