| 2021-09-18 | UFC Fight Night: Smith vs. Spann | Light Heavyweight | Tafon Nchukwi def. Mike Rodríguez | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2021-02-06 | UFC Fight Night: Overeem vs. Volkov | Light Heavyweight | Danilo Marques def. Mike Rodríguez | Technical Submission (rear-naked choke) | 2 | 4:52 |
| 2020-09-12 | UFC Fight Night: Waterson vs. Hill | Light Heavyweight | Ed Herman def. Mike Rodríguez | Submission (kimura) | 3 | 4:01 |
| 2020-08-22 | UFC on ESPN: Munhoz vs. Edgar | Light Heavyweight | Mike Rodríguez def. Marcin Prachnio | KO (elbow and punches) | 1 | 2:17 |
| 2019-12-21 | UFC Fight Night: Edgar vs. The Korean Zombie | Light Heavyweight | Da Un Jung def. Mike Rodríguez | KO (punches) | 1 | 1:04 |
| 2019-07-13 | UFC Fight Night: de Randamie vs. Ladd | Light Heavyweight | John Allan vs. Mike Rodríguez | No Contest (overturned) | 3 | 5:00 |
| 2018-12-15 | UFC on Fox: Lee vs. Iaquinta 2 | Light Heavyweight | Mike Rodríguez def. Adam Milstead | TKO (knee to the body and punches) | 1 | 2:59 |
| 2018-04-07 | UFC 223: Khabib vs. Iaquinta | Light Heavyweight | Devin Clark def. Mike Rodríguez | Decision (unanimous) (29–28, 30–27, 30–27) | 3 | 5:00 |