| 2020-08-01 | UFC Fight Night: Brunson vs. Shahbazyan | Catchweight | Jonathan Martinez def. Frankie Saenz | TKO (knee and punches) | 3 | 0:57 |
| 2019-03-23 | UFC Fight Night: Thompson vs. Pettis | Bantamweight | Marlon Vera def. Frankie Saenz | TKO (punches) | 1 | 1:25 |
| 2018-05-19 | UFC Fight Night: Maia vs. Usman | Bantamweight | Frankie Saenz def. Henry Briones | Decision (unanimous) (30–27, 30–27, 30–26) | 3 | 5:00 |
| 2017-12-09 | UFC Fight Night: Swanson vs. Ortega | Bantamweight | Frankie Saenz def. Merab Dvalishvili | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2017-01-15 | UFC Fight Night: Rodríguez vs. Penn | Bantamweight | Augusto Mendes def. Frankie Saenz | Decision (split) (28–29, 29–28, 29–28) | 3 | 5:00 |
| 2016-07-23 | UFC on Fox: Holm vs. Shevchenko | Bantamweight | Eddie Wineland def. Frankie Saenz | TKO (punches) | 3 | 1:54 |
| 2015-12-12 | UFC 194: Aldo vs. McGregor | Bantamweight | Urijah Faber def. Frankie Saenz | Decision (unanimous) (29–28, 29–28, 30–27) | 3 | 5:00 |
| 2015-08-08 | UFC Fight Night: Teixeira vs. Saint Preux | Bantamweight | Frankie Saenz def. Sirwan Kakai | Decision (split) (28–29, 30–27, 30–27) | 3 | 5:00 |
| 2015-02-22 | UFC Fight Night: Bigfoot vs. Mir | Bantamweight | Frankie Saenz def. Iuri Alcântara | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2014-08-16 | UFC Fight Night: Bader vs. Saint Preux | Bantamweight | Frankie Saenz def. Nolan Ticman | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |