| 2016-04-23 | UFC 197: Jones vs. Saint Preux | Lightweight | Kevin Lee def. Efraín Escudero | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2015-11-21 | The Ultimate Fighter Latin America 2 Finale: Magny vs. Gastelum | Lightweight | Leandro Silva def. Efraín Escudero | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2015-06-13 | UFC 188: Velasquez vs. Werdum | Lightweight | Efraín Escudero def. Drew Dober | Submission (standing guillotine choke) | 1 | 0:54 |
| 2015-02-14 | UFC Fight Night: Henderson vs. Thatch | Lightweight | Efraín Escudero def. Rodrigo de Lima | Decision (unanimous) (30–27, 30–27, 30–27) | 3 | 5:00 |
| 2014-09-13 | UFC Fight Night: Bigfoot vs. Arlovski | Lightweight | Leonardo Santos def. Efraín Escudero | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2012-04-21 | UFC 145: Jones vs. Evans | Lightweight | Mac Danzig def. Efraín Escudero | Decision (unanimous) (30–27, 30–27, 29–28) | 3 | 5:00 |
| 2011-12-30 | UFC 141: Lesnar vs. Overeem | Lightweight | Jacob Volkmann def. Efraín Escudero | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |
| 2010-09-15 | UFC Fight Night: Marquardt vs. Palhares | Catchweight | Charles Oliveira def. Efraín Escudero | Submission (rear-naked choke) | 3 | 2:25 |
| 2010-05-29 | UFC 114: Rampage vs. Evans | Lightweight | Efraín Escudero def. Dan Lauzon | Decision (unanimous) (29–27, 29–27, 29–27) | 3 | 5:00 |
| 2010-01-11 | UFC Fight Night: Maynard vs. Diaz | Lightweight | Evan Dunham def. Efraín Escudero | Submission (armbar) | 3 | 1:59 |
| 2009-09-19 | UFC 103: Franklin vs. Belfort | Lightweight | Efraín Escudero def. Cole Miller | TKO (punches) | 1 | 3:36 |
| 2008-12-13 | The Ultimate Fighter: Team Nogueira vs. Team Mir Finale | Lightweight | Efraín Escudero def. Phillipe Nover | Decision (unanimous) (29–28, 29–28, 29–28) | 3 | 5:00 |